I would say no... the bigger gecko will likely dominate the smaller one, controlling the food source, hides, etc. If you're housing geckos together, they should be of similar weight and length.
Yea, I think that it depends on the gecko too. Even with normal sized leos, it depends on if they are going to get along or not. We just watch ours very closely when we put new ones in together. As long as they arent harmful to eachother than I dont see why it would matter. I would just look very closely for dominance issues