Panacur Dosage Question

[Tanga]

One of my leos has tested positive for parasites. Panacur is the medication that I will be giving, although I'm a bit confused on this ML - MG conversion. I was given a syringe that only measures in cc's/mL. I was told the correct dosage amount would be just one notch size on the syringe, once a week for 3 weeks. Is this correct?

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So one notch length on this syringe would be equal to .025 mg?? :main_huh:

 

[robin]

best thing to do is contact your vet to find out exactly

 

[Cheaton]

ml and mg are only related based on the concentration of the solution. If you have a 1000 ml of a 10% solution then you have 100mg of Panacur in 1000ml of solution. So therefore, 100ml would equal 10mg and 10 ml would equal 1mg and 1ml would equal .1mg. Did your vet give you a solution? How much, and what is the percentage or ml/mg ratio? If you're unsure of that you should definitely call your vet. If you have a powder then you will make your own solution and have to do your own calculations.

The powder you can get from the pet store is a 22.2% panacur and a total of 1g of powder. So, if you had 100g of powder you would have 22.2g of panacur. that means in 1g of powder you have .222g of panacur, or 222mg of panacure.

I guess what i'm trying to say is. Milligrams and Milliliters are not the same milliliters is the total of the solution, milligrams is how much panacur is in the solution. You could give your lizard 10 ml of a 10% solution or 10ml of a 22.2 solution and you are giving them two different amounts of panacur.

There is no "conversion" from mg to ml. One "notch" on that syringe (assuming a notch is one small line) is .1ml. If your vet says that is .025mg then you can assume that the ratio is .10ml/.025mg which means you have a 25% solution. (.10ml/.025mg move both dcimals three spaces to the right you get 100/25 or 25%). If he means 1 large line as a "notch" then thats .5ml/.025mg. And that would be a 5% solution.

 

[Cheaton]

Ok just need to reiterate something I couldn't edit from my last post because i took too long. I wanted to summarize.


You cannot convert mg to ml or vise versa. One is a unit of volume (ml) and one is a unit of weight (mg). What you are dealing with is a ratio of Volume(ml)/Weight(mg). So 1 line on that syringe only equals .025mg if there is .025mg by weight of panacur in however much 1 line is.

 

[Tanga]

Thanks for the info Cheaton.
I found out my leo had parasites when I took a fecal sample to my college lab where they tested it out for free. Knowing that Panacur takes care of some parasitic infections I decided to get some at the petstore. It's a 10% solution.

 

[Tanga]

Okay, just looked at the medication. It's a 25 gram paste 10% (100mg/g)

I've never been good at conversions or math, so maybe somebody can chime in again and give me some help?

 

[Gecko]

You got the horse tube?

Are you sure the results were actually acurate and the worms were not from crickets, etc.?

The amount you need is probably very very small.

 

[PaulSage]

1. A cc (cubic centimeter) is equal to a mL (milliliter).

2. Panacur (fenbendazole) is not effective on all parasites that may be affecting a leopard gecko's digestive tract. (i.e. hookworm)

3. If you don't know which parasite(s) your gecko has, I would recommend finding that out first and using the appropriate medication prescribed by the vet. If you use the Panacur and later find out that it's ineffective against the parasite(s) actually infesting your gecko, you'd end up administering two different medications unnecessarily.

 

[Cheaton]

If it is a parasite that the panacur will fix then the following may help you give the proper dosage with your paste.

You have a 10% paste with 100mg/g.
And you have 25g total. So thats 2500mg total panacur. That means if you want to give a dose of .025 mg you just need to move some decimal points.

2500mg/25g move all decimal points 5 places to the left. .025mg/.00025gram. This is 25 thousanths of a gram of the paste. I think you're going to find it awfully hard to measure that unless you have a very very sensitive lab scale. However, if you take 1 gram of the paste (25mg) and dilute it into 100ml of water you will have 25mg/100ml. If you move the decimal points 3 places to the left you get .025mg/.1ml. That means 1 small line on that syringe would equal .025mg of panacur. If you want to make it easier for yourself to measure dosages then you could mix it into 500ml of water (half a liter) and draw .5ml at a time into the syringe (the first big line that says .5).

SO i'll summarize:

1 gram of paste into 100 ml of water gives you .025mg/.1 ml panacur/water ratio. OR 1 gram of paste into 500ml of water gives you .025mg/.5ml panacur/water.

 

[Golden Gate Geckos]

The way to calculate dosages is:

dose x weight divided by concentration

The correct dosage for Panacur is 25 miligrams per kilogram of body weight.
1 kilogram = 1000 grams.
So, let's say a gecko weighs 50 grams. 50 grams = 0.05 kilograms.
25 mg (dose) X 0.05 kg (weight) = 1.25 mg
1.25 mg divided by 10% (concentration) = 0.125 cc weekly

It will be very difficult for you to accurately measure this dose with the 3 cc syringe you have. See if you can get a 1 cc tuberculin syringe. Here is how you would measure the dose with that syringe:

 

[Tanga]

I appreciate the detailed information on the doses. I will try to pick up a smaller syringe at the lab today, while I'm doing that I'm going to bring another fecal sample in to determine exactly what kind of parasite it is so I know I'm using the right medication. We have an abundance of reptiles in the zoology lab and many of them are or have been on panacur for precaution, so I'm guessing the students that care for them know what they're doing.
Thanks again Paul, Cheaton, & Marcia

 

[Country Gecko]

Somewhat confused on this dosage calculation???

Hi Marcia,

I was just reading a few random threads and came across this dosage calculation. I notice that it says "The correct dosage for Panacur is 25 miligrams per kilogram of body weight". However, if this is the case, wouldn't your example be complete at the point where "25 mg (dose) X 0.05 kg (weight) = 1.25 mg"?

I realize the Panacur/Safegaurd is a 10% solution, and if there is a further step in this calculation wouldn't you multiply by ten rather than divide to reach 100%?

Also, here's a link to a calculator that appears to follow my thoughts in my first paragraph above http://www.sandfiredragonranch.com/resources/index.html

Thanks in advance for your reply,
Glenn

The way to calculate dosages is:

dose x weight divided by concentration

The correct dosage for Panacur is 25 miligrams per kilogram of body weight.
1 kilogram = 1000 grams.
So, let's say a gecko weighs 50 grams. 50 grams = 0.05 kilograms.
25 mg (dose) X 0.05 kg (weight) = 1.25 mg
1.25 mg divided by 10% (concentration) = 0.125 cc weekly

It will be very difficult for you to accurately measure this dose with the 3 cc syringe you have. See if you can get a 1 cc tuberculin syringe. Here is how you would measure the dose with that syringe:

 

[JordanAng420]

This is a great example of a 1mL syringe...except it's backwards 0.1ml (1 tenth of an mL) is the first notch, not the last. And 1.0 mL is the very last notch nearest to the plunger. Great info. though

 

[JordanAng420]

This is a great example of a 1mL syringe...except it's backwards 0.1ml (1 tenth of an mL) is the first notch, not the last. And 1.0 mL is the very last notch nearest to the plunger. Great info. though

Forget what I just said. I just realized the damn syringe was upside down. My bad.

 

[Ccrashca069]

If all else fails contact your nearest herp vet and ask or if I remember to ask the 2 herp vets at the hospital on Tuesday I can let you know how they calculate it.

 

[Golden Gate Geckos]

I was just reading a few random threads and came across this dosage calculation. I notice that it says "The correct dosage for Panacur is 25 miligrams per kilogram of body weight". However, if this is the case, wouldn't your example be complete at the point where "25 mg (dose) X 0.05 kg (weight) = 1.25 mg"?

I realize the Panacur/Safegaurd is a 10% solution, and if there is a further step in this calculation wouldn't you multiply by ten rather than divide to reach 100%?

I understand what you are saying. If a concentration is stated in percent, multiply the percent by 10 to get the concentration in mg/ml. For instance, Baytril comes as 2.27% solution. Multiply 2.27 by 10, and there are 22.7 mg/ml.

ANY medication is calculated:

dose X weight / concentration

 

[bitterbeauty]

I have been treating one of my geckos for parasites with the same medicine and I was told one drop on the nose once a week for 3 weeks. I was given the same syringe.

 

[Country Gecko]

Hi Marcia,

Yes, I believe that is right! If it is a 10% solution, you would divide by 0.1 since it is 0.1 of 1.0 (1 being 100%) if that makes sense? It would also make sense that you multiply times 10 (or divide by 0.1) if it is a diluted solution down to 10%.

I understand what you are saying. If a concentration is stated in percent, multiply the percent by 10 to get the concentration in mg/ml. For instance, Baytril comes as 2.27% solution. Multiply 2.27 by 10, and there are 22.7 mg/ml.

ANY medication is calculated:

dose X weight / concentration